Drug Discovery Today, 2009, 14(3-4), 134-146

 

Micro- and nanofluidic systems for high-throughput biological screening

 

Jongin Hong, Joshua B. Edel and Andrew J. deMello

 

High-throughput screening (HTS) is a method of scientific experimentation widely used in drug discovery and relevant to the fields of biology. The development of micro- and nanofluidic systems for use in the biological sciences has been driven by a range of fundamental attributes that accompany miniaturization and massively parallel experimentation. We review recent advances in both arraying strategies based on nano/microfluidics and novel nano/microfluidic devices with high analytical throughput rates.

 

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T64-4V2PHY6-1&_user=217827&_coverDate=02%2F28%2F2009&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000011279&_version=1&_urlVersion=0&_userid=217827&md5=508117e1778bd1f69202b0850adf2f1e

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